Coronary Artery Disease and Inherited Real Risk of CAD
نویسندگان
چکیده
The genetic alteration of mit-DNA affects the mitochondrial activity, main responsible of cell respiration in biological systems. The chance to investigate, indirectly and through bed-side evaluation, the mitochondria functionality and microvessels dynamics opens new ways to understand and face the very beginning states of Coronary Artery Disease, CAD, even silent and not yet clinically diagnosed, and of the inherited real risk of CAD.
منابع مشابه
Using Combined Descriptive and Predictive Methods of Data Mining for Coronary Artery Disease Prediction: a Case Study Approach
Heart disease is one of the major causes of morbidity in the world. Currently, large proportions of healthcare data are not processed properly, thus, failing to be effectively used for decision making purposes. The risk of heart disease may be predicted via investigation of heart disease risk factors coupled with data mining knowledge. This paper presents a model developed using combined descri...
متن کاملThe association between NFKB1 -94ATTG ins/del and NFKB1A -826C/T genetic variations and coronary artery disease risk
Coronary artery disease (CAD) is considered as a chronic inflammatory disease initiated from early childhood. Nuclear factor κB (NF κB) and κB1A (NF κB1A) are the key regulators of inflammatory responses. The NFKB1 -94ATTG ins/del and NFKB1A -826C/T polymorphisms may contribute to the development of CAD. The aim of the present study was to investigate the association of these polymorphisms wit...
متن کاملCoronary Artery Disease and CAD Inherited Real Risk
The genetic alteration of mit-DNA affects the mitochondrial activity, main responsible of cell respiration in biological systems. The chance to investigate, indirectly and through bed-side evaluation, the mitochondria functionality, with the support or chaos theory, opens new ways to understand and face the very beginning states of Coronary Artery Disease – CAD, even silent and not yet clinical...
متن کاملStudy of the correlation between ACE gene polymorphism and coronary artery disease
Introduction: Angiotensin converting enzyme (ACE) is an exopeptidase that converts Angiotensin I to Angiotensin II. Angiotensin II is a potent vasoconstrictor and releases aldosterone, and have a critical role in hypertension. In this study, ACE insertion / deletion (I/D) polymorphism and ACE activity was determined in patients with coronary artery disease (CAD) and normal subjects. The corr...
متن کاملA preliminary study of the association between the ABCA1 gene promoter DNA methylation and coronary artery disease risk
Coronary artery disease (CAD) is a common health problem in Iranian population. ATP binding cassette transporter A1 (ABCA1) plays central role in the efflux of the cholesterol from peripheral tissues back to liver. Inactivation of ABCA1 by epigenetic change such as DNA methylation may contribute to the development of CAD. The present study investigated the association between promoter DNA methy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011